A/Prof. Torsten Seemann
The University of Melbourne
De novo genome assembly
Next generation sequencing & bioinformatics
Monday 2 July 2018
A/Prof. Torsten Seemann is the lead bioinformatician at Melbourne Bioinformatics (formerly VLSCI) and Doherty Applied Microbial Genomics, both at the University of Melbourne. His work uses bioinformatics and genomics to better understand the spread and evolution of bacterial pathogens and antimicrobial resistance. He is best known for his software tools which are used internationally, and he is a strong supporter of open science.
How do we generate the genome sequence of our favourite organism? In this talk I will introduce the problem of de novo genome assembly; describe the strategies and caveats of the way the problem is tackled; and outline ways to assess the results. The related problems of transcriptome and metagenome assembly, and how the latest technologies are transforming de novo assembly, will also be touched upon.