Project Description

Dr Joshua W.K. Ho

Head, Bioinformatics and Systems Medicine Laboratory
Victor Chang Cardiac Research Institute

Bioinformatics analysis of single-cell RNA-seq data

Next generation sequencing & bioinformatics

Tuesday 3 July 2018

Dr Joshua Ho is the Head of Bioinformatics and Systems Medicine Laboratory at the Victor Chang Cardiac Research Institute. He is also an NHMRC Career Development Fellow and a Heart Foundation Future Leader Fellow. Joshua completed his BSc (Hon 1, Medal) and PhD in Bioinformatics from the University of Sydney, and undertook postdoctoral research at the Harvard Medical School. His current research focuses on developing fast and reliable bioinformatics methods to identify the genetic cause and mechanism of inherited heart diseases, using a range of approaches such as whole genome sequencing, single-cell RNA-seq, ChIP-seq, machine learning, systems biology, cloud computing, and software testing and quality assurance. His research excellence has been recognised by the 2015 NSW Ministerial Award for Rising Star in Cardiovascular Research, the 2015 Australian Epigenetics Alliance’ Illumina Early Career Research Award, and the 2016 Young Tall Poppy Science Award.

In this lecture we will explore the characteristics of single-cell RNA-seq data, and discuss current bioinformatics methods and software that have been designed to analyse these data.