Project Description

Dr Alicia Oshlack

 

Head of Bioinformatics
Murdoch Childrens Research Institute

Analysing RNA-seq data: differential expression and beyond

Next generation sequencing & bioinformatics

Tuesday 5 July 2016

In this talk I will give a basic overview of the statically and computational analysis for performing differential expression using RNA-seq data. I will discuss the steps in a standard analysis for both well studied organisms, like humans, and more exotic organisms, without a sequenced genome.

Dr Alicia Oshlack is a NHMRC career development fellow and is the Head of Bioinformatics at the Murdoch Childrens Research Institute where she leads a team of 10 students, postdocs and research assistants. Alicia did a PhD in astrophysics and has been working in the field of Bioinformatics for more than 12 years. She is best known for her body of work developing methods for the analysis of transcriptome data. She also works in epigenomics and clinical genomics. Alicia has also built an extensive collaborative network with many national and international research groups uncovering molecular mechanisms of development and disease using a variety of genomic approaches. Alicia is on the editorial board of Genome Biology, was awarded the Australian Academy of Science Gani Medal for human genetics in 2011 and the Lorne Genome Conference Millennium Science Award in 2015.