Category: Uncategorized

Galaxy Australia: advanced bioinformatics within a biologist-friendly interface – Igor Makunin

Galaxy Australia https://usegalaxy.org.au is a national service designed for the analysis of genome scale data, with an emphasis on high throughput sequencing. Galaxy Australia provides preinstalled bioinformatic tools and public data, such as reference genomes. The Galaxy web interface does … Read more


An introduction to Galaxy with the NeCTAR Genomics Virtual Laboratory – Igor Makunin

The Galaxy platform is one of the world’s most popular and fastest growing bioinformatics web-based interfaces. With Galaxy, biologists can access a huge range of bioinformatics tools, using user-friendly and intuitive graphical interfaces. Galaxy also captures and records analysis pipelines … Read more


Completing bacterial genomes using long sequencing reads: working towards the perfect genome assembly – Ryan Wick

Genome assemblers are tools which aim to reconstruct an original genome from sequencing reads. A ‘perfect’ assembler would take only reads as input and output a complete, error-free genome. This goal is usually impossible with short reads alone, but adding … Read more


Bioinformatics in industrial research – Benjamin Goudey

Industrial research is all about conducting research within a company to develop new products, enhance existing ones, or identify new areas the company should pursue. The increasing amount of high-throughput biological data being generated in healthcare and life sciences, and … Read more


Random forest and its application to genome-wide association studies – Arash Bayat

GWAS is about computing association power of SNPs with the phenotype of interest. Traditional GWAS tends to look at each SNP independent from other SNPs when measuring association power. However, it has been discovered that there are SNPs that interact … Read more


Extracting knowledge from models trained on biological data to measure performance and improve understanding of the system – Alexandra Essebier

Extracting knowledge from statistical and machine learning approaches is a challenge faced by many researchers including those in the field of bioinformatics. A large amount of data is now available that captures multiple aspects of human biology at the cellular … Read more


Applications of long-read sequencing in microbial genomics – Leah Roberts

The advent and continual advancement of whole genome sequencing technology has dramatically improved our ability to investigate bacterial genomes at the highest possible resolution. However, despite their small size, many bacterial genomes are unable to be completely resolved using short-read … Read more


Machine learning applications in functional annotation – Marina Naval Sanchez

Functional genomics is in the forefront of the application of machine learning methods to predict enhancers and cis-regulatory regions as well as to predict the impact of SNPs in regulatory regions at the level of downstream function, namely open-chromatin and … Read more


Next-generation sequencing – technology overview – Christopher Noune

The “Next-Generation Sequencing” landscape is one of constant change, with new and emerging technologies competing with established methods and platforms. Chris talks about the sequencing technologies that currently dominate the sequencing landscape, as well as those that are poised to … Read more


The application of long read sequencing technologies to animal agriculture – Elizabeth Ross

Long read sequencing is changing genomics as we know it. The possibilities and economics of new technologies will drive a second genomic revolution in non-model organisms. Tasks such as the assembly of ultra-high quality genomes that use to take years, … Read more