Project Description

Dr Katia Nones


QIMR Berghofer Medical Research Institute

Whole-genome sequencing and cancer genomics

Next generation sequencing & bioinformatics

Monday 1 July 2019

Dr Katia Nones is a Senior Research Officer at QIMR Berghofer Medical Research Institute. She is an expert on the interpretation of next generation sequencing and array data for cancer research. She was a member of the Australian International Cancer Genome Consortium (ICGC) and is a member of the Australian Genomics Heath Alliance. Her research has been focused on using genomic, epigenomic and expression data in a multi-disciplinary field with a particular interest in cancer research. She uses whole-genome sequencing to identify novel driver genes and identify potentially druggable targets. She also uses tumour specific mutations to identify mutational signatures associated to processes linked to tumour development. These signatures can also indicate treatment options.

In this talk I will give some examples of how we used the whole-genome sequencing data in our research to identify the tumour specific mutations. I will also show examples of how the pattern of these mutations can give us information about driver genes in different cancer types and give us clues about potential treatment options.